2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-125446S
    2-Hydroxymethyl olanzapine-d3
    2-Hydroxymethyl olanzapine-d3 (LY-290411-d3) is a deuterium labeled 2-Hydroxymethyl olanzapine. 2-Hydroxymethyl olanzapine is a metabolite of Olanzapine..
    2-Hydroxymethyl olanzapine-d<sub>3</sub>
  • HY-131964R
    Imidacloprid-urea (Standard)
    Sodium ethylparaben (Standard) is the analytical standard of Sodium ethylparaben. This product is intended for research and analytical applications. Sodium ethylparaben (Sodium ethyl 4-hydroxybenzoate) acts as a water soluble antiseptic usually employed as safe for cosmetics.
    Imidacloprid-urea (Standard)
  • HY-133675S
    Mono(5-carboxy-2-ethylpentyl) phthalate-d4
    Mono(5-carboxy-2-ethylpentyl) phthalate-d4 (MECPP-d4) is a deuterium labeled Mono(5-carboxy-2-ethylpentyl) phthalate (HY-133675). Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di-(2-ethylhexyl) phthalate (DEHP). Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking.
    Mono(5-carboxy-2-ethylpentyl) phthalate-d<sub>4</sub>
  • HY-135387
    4-Desmethyl Istradefylline
    4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
    4-Desmethyl Istradefylline
  • HY-W015788R
    1-Phenylethane-1,2-diol (Standard)
    1-Phenylethane-1,2-diol (Standard) is the analytical standard of 1-Phenylethane-1,2-diol. This product is intended for research and analytical applications. 1-Phenylethane-1,2-diol (Styrene Glycol) is a benzyl diol compound, which is the major metabolite of Styrene. 1-Phenylethane-1,2-diol can be oxidized to hydroxyl ketone (2-hydroxy-1-phenylethan-1-one) selectively with variety of catalysts, including organocatalysts, metal complexes, non-noble metal oxides, bimetallics[1][2][3].
    1-Phenylethane-1,2-diol (Standard)
  • HY-W743473
    Cefetamet-d3
    Cefetamet-d3 (Ro 15-8074-d3; Deacetoxycefotaxime-d3) is the deuterium labeled Cefetamet (HY-A0111). Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis.
    Cefetamet-d<sub>3</sub>
  • HY-131466R
    N-Methyl Palbociclib (Standard)
    Hydroxyurea (Standard) is the analytical standard of Hydroxyurea. This product is intended for research and analytical applications. Hydroxyurea is a cell apoptosis inducer that inhibit DNA synthesis through inhibition of ribonucleotide reductase. Hydroxyurea shows anti-orthopoxvirus activity.
    N-Methyl Palbociclib (Standard)
  • HY-W700643
    Di-N-desethyl amiodarone hydrochloride
    Di-N-desethyl Amiodarone hydrochloride is a metabolite of Amiodarone (HY-14187). Di-N-desethyl Amiodarone hydrochloride is a strong inhibitor of the respiratory chain.
    Di-N-desethyl amiodarone hydrochloride
  • HY-129903
    N-Desethyl vardenafil
    N-Desethyl vardenafil is the major metabolite of Vardenafil (HY-B0442) and can be detected in human urine.
    N-Desethyl vardenafil
  • HY-118614R
    β-Nicotyrine (Standard)
    β-Nicotyrine (Standard) is the analytical standard of β-Nicotyrine. This product is intended for research and analytical applications. β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid.
    β-Nicotyrine (Standard)
  • HY-121745
    Phosmet oxon
    Phosmet oxon (Imidoxon) is a main and toxic metabolite of phosmet. Phosmet is a cholinesterase inhibitor insecticide used on pome and stone fruits.
    Phosmet oxon
  • HY-138627B
    AST5902 mesylate
    AST5902 mesylate is a principal metabolite of Alflutinib, exhibiting significant antineoplastic activity. AST5902 mesylate contributes to the overall pharmacological effects in the treatment of non-small cell lung cancer. AST5902 mesylate is involved in the response to activating EGFR mutations and can help overcome EGFR T790M drug-resistant mutations.
    AST5902 mesylate
  • HY-131261
    Ibuprofen alcohol
    Ibuprofen alcohol, a nonsteroidal antiinflammatory agent (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs).
    Ibuprofen alcohol
  • HY-135910R
    3,4-Dehydro Cilostazol (Standard)
    3,4-Dehydro Cilostazol (Standard) is the analytical standard of 3,4-Dehydro Cilostazol. This product is intended for research and analytical applications. 3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study.
    3,4-Dehydro Cilostazol (Standard)
  • HY-113040
    (17S,18R)-Epoxyeicosatetraenoic acid
    17(18)-EpETE, a 17(18)-epoxyeicosatetraenoic acid, is a metabolize of Eicosapentaenoic acid (HY-B0660). 17(18)-EpETE stimulates K+ outward currents. 17(18)-EpETE has relaxing effects on arterial and airway smooth muscles in human lung.
    (17S,18R)-Epoxyeicosatetraenoic acid
  • HY-W336012S
    Metoprolol EP impurity O-d7 hydrochloride
    Metoprolol EP impurity O-d7 (hydrochloride) is the deuterium labeled 3,3'-(Isopropylazanediyl)bis(1-(4-(2-methoxyethyl)phenoxy)propan-2-ol).
    Metoprolol EP impurity O-d<sub>7</sub> hydrochloride
  • HY-137236
    6β-Hydroxy metandienone
    6β-Hydroxy metandienone is an anabolic androgenic steroid metabolite of Metandienone.
    6β-Hydroxy metandienone
  • HY-143951S
    Disulfiram impurity 1-d10
    Disulfiram impurity 1-d10 is the deuterium labeled Disulfiram impurity 1.
    Disulfiram impurity 1-d<sub>10</sub>
  • HY-B0601R
    Tafluprost acid (Standard)
    		Chemical
    Tectoquinone (Standard) is the analytical standard of Tectoquinone. This product is intended for research and analytical applications. Tectoquinone (2-Methylanthraquinone) is a SARSCoV-2 main protease inhibitor against COVID-19. Tectoquinone exhibits strong mosquito larvicidal activity with the LC50 values of 3.3 and 5.4 μg/ml against A. aegypti and A. albopictus in 24 h, respectively.
    Tafluprost acid (Standard)
  • HY-W740380
    21-Carboxylic acid triamcinolone acetonide
    21-Carboxylic acid triamcinolone acetonide is a metabolite produced in the body after oral administration of [14C]-triamcinolone acetonide.
    21-Carboxylic acid triamcinolone acetonide
Cat. No. Product Name / Synonyms Application Reactivity